Past events

IID Seminar | Correlates of risk of TB disease and their back-translation into animal models

Summary Immune correlates of risk of TB disease have recently been identified in human clinical trials. These correlates indicate that, years before TB disease develops, there is alteration in the host-immune environment which is associated with risk of TB disease. Perhaps these alterations render the immune environment permissive to mycobacterial infection or increased growth, or […]

Post-viva seminar | The development of a mathematical modelling framework to translate TB vaccine responses between species and predict the most immunogenic dose in humans using animal data

Summary Vaccine dosing decision making employs relatively antiquated methods compared to the methods employed for drug dosing decision making. As such, we may be discarding vaccine candidates and wasting considerable resources. This failure to use modern methods may, in part, be due to the complexities in measuring a biomarker of vaccine efficacy and defining the […]

Seminar | Latent Tuberculosis Infection: Advances and Challenges

Summary Dr. Sterling received his medical degree from the Columbia University College of Physicians Surgeons, completed his residency training in internal medicine at Columbia-Presbyterian Medical Center, and fellowship training in infectious diseases at Johns Hopkins Hospital. He joined the Johns Hopkins faculty in 1998, and moved to Vanderbilt in 2003. He is the director of […]

Inaugural lecture | Medicinal Maths: a career modelling bugs

Details Speaker: Professor Richard White, Professor of Infectious Disease Modelling Date: Thursday 9 November 2017 Time: 17:15 – 19:00 Venue: Manson Lecture Theatre, Keppel Street Followed by a drinks reception in the North Courtyard Atrium. The lecture will be streamed live. Free and open to all. No registration is required. Entrance is on a first come, first serve […]

ITD Seminar | Why does BCG protect against tuberculosis… and why does it not?

Summary BCG vaccination often fails to protect against TB, hence the need for a new TB vaccine. But sometimes it works. What’s going on, immunologically, in both cases and how can this information help us develop a better vaccine? Details Speaker: Dr Steven Smith, LSHTM Date: 8 November 2017 Time: 12.30 pm Venue: Lucas Room – LG81 Watch […]

Seminar | Financial hardship from drug resistant tuberculosis in Rio de Janeiro, Brazil; A patient cost survey

Summary Even though tuberculosis (TB) diagnosis and treatment is free, households affected by drug resistant (DR) TB incur hidden costs from direct “out of pocket” expenses for consultations, transport, additional food and natural remedies, as well as lost income from personal and family members’ time away from work. The global TB strategy prioritises protecting all […]

Union Conference | TB Centre attendance

TB Centre members presenting at Union The 48th Union World Conference on Lung Health is being held in Guadalajara, Mexico, from 11–14 October 2017, and TB Centre members at the London School of Hygiene & Tropical Medicine have various posters, oral presentations and will be speaking at symposia. Use this link to download a PDF of the […]

Seminar | My wife has drug-resistant TB; and what of me and our children?

Co-hosted with the AMR Centre Summary The last two decades have seen huge leaps in the recognition and diagnosis of MDR-TB and therapeutic management is gradually catching up. Nevertheless, for an affected household the identification of an individual with MDR-TB using a novel diagnostic and the initiation of an exciting new treatment regimen, is only […]

PhD upgrading seminar | Accelerating the development of effective vaccines for protection against Mycobacterium tuberculosis

Overview Immunology and Infection PhD Upgrading Seminar “Accelerating the development of effective vaccines for protection against Mycobacterium tuberculosis”. Speaker: Hannah Painter. Supervisors: Helen Fletcher, Andrea Zelma and Rajko Reljik Details Speaker: Hannah Painter Date: Thursday 28 September 2017, 12:30 Venue: Bennett Room LG80, Keppel Street

Pre-viva seminar | Investigating Mycobacterium tuberculosis transmission in rural Malawi

Overview Current control strategies are failing to contain the tuberculosis (TB) epidemic and are limited by our lack of understanding of Mycobacterium tuberculosis (M.tb) transmission dynamics, especially in HIV-prevalent settings. M.tb infection in children aged under 5 years of age indicates recent transmission, acting as a sentinel for infectious (typically adult) TB and highlights recent failures in community control […]