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January 2018

Inside this month’s TB Centre Newsletter: 

1. Registration for World TB Day & Steve Lawn Memorial Lecture
2. Seminars
3. Steve Lawn Memorial Prize winner
4. Recent publications – blogs
5. TB research grant award – congratulations!
6. Conferences in 2018
7. WHO NewsFlash
8. Jobs

Registration is open!

Steve Lawn Memorial Lecture – 22 March 2018

The TB Centre will be hosting the second series of lecture, to be presented by Professor Liz Corbett, organised in honour of the life and work of Stephen Lawn. Steve was Professor of Infectious Diseases and Tropical Medicine at the School and an active member of the TB Centre, and worked closely with the Desmond Tutu HIV Centre at the University of Cape Town (UCT), where he was based from 2005 to 2012. Information about the first memorial lecture can be found here.

Register for this year’s lecture

Speaker: Professor Liz Corbett (London School of Hygiene & Tropical Medicine)
Title: Re-imagining HIV and TB Screening
Chair: Professor Tony Harries (IUALTD and London School of Hygiene & Tropical Medicine Honorary Fellow)
Date: 22 March
Time: 17:15 – 18:30 GMT, followed by a drinks reception
Venue: John Snow Lecture Theatre, Keppel Street

World TB Day Symposium – 23 March 2018

In March each year, the world commemorates the day in 1882 when Dr Robert Koch announced his discovery of Mycobacterium tuberculosis. We take this opportunity each year to highlight contemporary research innovation and future challenges in a one-day symposium co-organised by LSHTM and UCL.

Register for this year’s symposium

Speakers: List of speakers
Theme: The Challenge of Antimicrobial Resistance
Date: 23 March
Time: 9:00 – 16:30 GMT, with drinks reception afterwards
Venue: John Snow Lecture Theatre, Keppel Street

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Upcoming Seminars

February:
Dr Nick Furnham, LSHTM – Molecular consequences of genomic variation associated with drug resistance in TB and malaria
Thursday 1 February 2018, 12.45 pm (UK time), Manson Lecture Theatre, Keppel Street

Members of the TB Centre will be presenting at the first UCL-AHRI scientific symposium – UCL-AHRI Symposium: Towards HIV and TB elimination in South Africa
Monday 12 February, 9:45 am – 7:00 pm (UK time), UCL, Roberts Building, Malet Place, London WC1E 7JE

March:
Dr Leonardo Martinez, Stanford University School of Medicine Pediatric Tuberculosis in sub-Saharan Africa: Observations from Uganda and South Africa
Tuesday 20 March 2018, 12.45 pm (UK time), LG7, Keppel Street

You can find more information about upcoming events on our website.

Professor Stephen Lawn Memorial Prize | 2018 Winner

 

The Stephen Lawn Memorial Lecture will be held at the London School of Hygiene and Tropical Medicine in London on Thursday 22 March. This year Professor Liz Corbett from Malawi and the London School will be giving the Stephen Lawn Memorial lecture.

This lecture is linked to the Stephen Lawn Memorial Fund, which also includes a Prize for an early researcher conducting work focused on reducing the disease burden of HIV associated TB in Africa.

This year we announce the first winner of the Stephen Lawn Memorial Prize, Dr Leonardo Martinez, who will be attending the lecture to receive his award, and giving a seminar on his research.

Read more.

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LSHTM publication blogs

A global study reveals new TB mutations that could transform tests for drug resistance

Multi drug-resistant TB is now found in almost all countries around the world. Even worse, incurable TB with resistance to all the locally available drugs has been reported in several countries, including countries with a high burden of disease such as India and South Africa. Complete resistance to the cocktail of antibiotics used to treat TB is an alarming and realistic prospect. What can be done?

The paper and blog by Taane Clarke can be read here.

The blog was also picked up by Reuters, and is receiving wide coverage.

Understanding mechanisms of tuberculosis disease severity

Tuberculosis disease, caused by Mycobacterium tuberculosis bacterial bugs, continues to have a profound impact on global health. In 2016 there were an estimated 10.4 million new cases and 1.7 million deaths, making tuberculosis disease the foremost cause of mortality from a single infectious agent. Vital in the fight against the disease is understanding how different bug strain-types affect disease severity. By analysing 16 well characterised strains from around the world, it was possible to identify modifications in the DNA genetic code that are thought to control how genes are “switched” on and off. Identified differences could explain disparities in known virulence and pathogenicity, and ultimately lead to improved management and control of the infectious disease.

Read the full blog here.

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LSHTM News | TB research grant

 

Dr Helen Ayles and colleagues have just signed the grant agreement for a large new grant from EDCTP looking at the effect of PopART intervention on TB.

The grant “Tuberculosis Reduction through Expanded Anti-retroviral Therapy and TB screening” (TREATS) is a 4 year grant of Euro 12,902,402 to a consortium led by LSHTM and including Imperial College, University of Sheffield, KNCV, The Union, Zambart, Health Systems Trust, Delft diagnostics and Qiagen.

The work includes establishing an adolescent cohort to measure incidence of infection, TB prevalence surveys and implementation science including qualitative assessment of the PopART intervention. A kick off meeting of the consortium was held in November 2017 in London and the team are hoping to start field work in the next few months.

An application for a full time research Fellow in London to join the team can be found in the jobs section below – research fellow in TB/HIV Epidemiology.

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External News | Conferences

SA TB Conference 2018 (Jun)

The 5th SA TB Conference in Durban, South Africa will take place between 12 – 15 June 2018.  The conference focuses on strategies and activities to end the TB epidemic once and for all.

Early registration and abstract submission closes on 31 January, and conference registration closes 31 May.

More details.

TB 2018 (July)

TB 2018 is an official pre-conference of the 22nd International AIDS Conference (AIDS 2018). The meeting will take place Sunday, 22 July 2018, at the RAI Amsterdam Convention Centre, just prior to AIDS 2018.

It is co-hosted by the International AIDS Society (IAS) in collaboration with the Stop TB Partnership and the United States Agency for International Development (USAID).

The abstract submission deadline is 5 February.

More details.

The Union World Conference 2018 (Oct)

The 49th Union World Conference on Lung Health in The Hague, The Netherlands, will take place between 24 – 27 October 2018 and bring together researchers, global advocates, scientists, healthcare professionals, students and community members working on all aspects of lung health.

The conference theme, Declaring Our Rights: Social and Political Solutions, highlights that to eliminate TB and achieve the health-related Sustainable Development Goals requires a coordinated public health response driven by the human rights of each individual.

The deadline for submissions of abstracts, symposia, post-graduate courses and workshops is 17 April.

More details.

TSRU 2018 meeting (Oct)

The TSRU 2018 has been postponed from April to October 2018, to benefit from a proposed TB scientific pre-conference that will be organised preceding the Union Conference in The Hague (above).

Also this year, since TB 2018 will be organised (preceding the AIDS conference – above), the TSRU can be be aligned with one of these meetings.

A group of sessions will be available for TSRU, to maximize TSRU’s visibility. The conference dates, abstract deadlines and all other relevant practical information will be shared with the TSRU community shortly. Abstracts that have already been submitted will be considered for the conference in October.

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External news | Global TB Programme 

WHO NewsFlash. 17 January 2018 | Geneva: Civil society representatives met with WHO leadership in Geneva, on 15-16 January 2018, with the aim of strengthening collaboration to end TB.

More details.

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Jobs

LSHTM Department of Clinical Research are seeking a research fellow in TB/HIV Epidemiology. More information can be found here.

The deadline for this application is 11 February 2018

LSHTM EPH Faculty are seeking to appoint up to four LSHTM Fellows at the Assistant Professor level funded by the LSHTM and Wellcome Institutional Strategic Support Fund. More information can be found here.

The deadline for this application is 26 February 2018.

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