Journal club | Household-Contact Investigation for Detection of Tuberculosis in Vietnam

Summary The TB Centre journal clubs allow staff and students the opportunity to discuss some of the latest research. They are a great opportunity to share knowledge and foster relationships across research disciplines, and we welcome attendance to all who are interested. This journal club session will be discussing the paper by Greg Fox in […]

Stephen Lawn Memorial Lecture 2018

Held by the London School of Hygiene & Tropical Medicine and the University of Cape Town in partnership with the International Union Against Tuberculosis and Lung Disease (The Union). Supported by The Lancet. The Lecture will be followed by a reception. Speaker: Professor Liz Corbett (London School of Hygiene & Tropical Medicine) Title: Re-imagining HIV and TB […]

Seminar | Pediatric Tuberculosis in sub-Saharan Africa: Observations from Uganda and South Africa

Summary Abstract: Tuberculosis is a leading cause of global childhood mortality however epidemiological knowledge of pediatric tuberculosis lags far behind that of adult tuberculosis. As a consequence, pragmatic approaches to guide case-finding and prevention strategies for young children in high-burden settings are lacking. This presentation describes two recent prospective cohort studies from sub-Saharan Africa that […]

Seminar | Bern-Thomas Nyang’wa – Title TBC

Details Speaker: Bern-Thomas Nyang’wa Date: 9 March 2018 Time: 12:45 – 14:00 Venue: TBC

ITD seminar | Journey into sub-Saharan Africa HIV co-infections, TB and CMV

Details Speaker: Dr Matthew Bates, School of Life Sciences, University of Lincoln Hosted by Dr Ursula Gompels Date: Thursday 8 March 2018 Time: 12:45 pm Venue: Manson Lecture Theatre, Keppel Street

ITD seminar | Molecular consequences of genomic variation associated with drug resistance in TB and malaria

Summary Genomic studies of Mycobacterium tuberculosis bacteria have revealed loci associated with resistance to anti-tuberculosis drugs. However, the molecular consequences of polymorphism within these candidate loci remain poorly understood. The talk will summarise the development and findings of a new computational protocol to quantify the effects of point mutations conferring resistance to three major anti-tuberculosis […]

Seminar | Treating 22 million patients for free – lessons learned

Resuscitating primary health care services in Pakistan and integrating vertical (TB) programme service delivery: experiences in setting up a public-private partnership model that has provided free treatment to 22 million patients Dr Riaz Memon is a senior civil servant and head of PPHI Sindh, a public-private partnership which has been contacted to run primary health services for a province […]

IID Seminar | Correlates of risk of TB disease and their back-translation into animal models

Summary Immune correlates of risk of TB disease have recently been identified in human clinical trials. These correlates indicate that, years before TB disease develops, there is alteration in the host-immune environment which is associated with risk of TB disease. Perhaps these alterations render the immune environment permissive to mycobacterial infection or increased growth, or […]

Post-viva seminar | The development of a mathematical modelling framework to translate TB vaccine responses between species and predict the most immunogenic dose in humans using animal data

Summary Vaccine dosing decision making employs relatively antiquated methods compared to the methods employed for drug dosing decision making. As such, we may be discarding vaccine candidates and wasting considerable resources. This failure to use modern methods may, in part, be due to the complexities in measuring a biomarker of vaccine efficacy and defining the […]

Seminar | Latent Tuberculosis Infection: Advances and Challenges

Summary Dr. Sterling received his medical degree from the Columbia University College of Physicians Surgeons, completed his residency training in internal medicine at Columbia-Presbyterian Medical Center, and fellowship training in infectious diseases at Johns Hopkins Hospital. He joined the Johns Hopkins faculty in 1998, and moved to Vanderbilt in 2003. He is the director of […]